A Second Generation Covid-19 Vaccine

A Second Generation Covid-19 Vaccine
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The more COVID–19 vaccines that work, the sooner we can end the pandemic

We are currently seeking a diverse group of volunteers to help in the research of an investigational vaccine to protect against the SARS-CoV-2 virus.

ImmunityBio's COVID-19 Vaccine Candidate: A Second-Generation Human Adenovirus (hAd5) Vaccine

Why the Second Generation Covid-19 Vaccine

  • Long-term protection – ImmunityBio’s viral-vector vaccine candidate targets both spike (S) and nucleocapsid (N) SARS-CoV-2 proteins to generate B and T cell memory to these antigens and, potentially, long-term immunity to the virus.
  • Multiple administration methods – The same vaccine has the potential to be administered three different routes to activate the entire immune system and provide T cell, B cell memory, and mucosal protection


ImmunityBio, Inc. is enrolling healthy volunteers in a clinical trial of a COVID-19 vaccine that can be given in multiple ways – by injection, a capsule, or a liquid. The trial is designed to study the optimal combination of administration route and dose for maximizing immune response to the COVID-19 virus.

Volunteers in the study will receive an initial injection of the vaccine candidate, followed by an oral capsule to be swallowed or a liquid dose administered under the tongue. Volunteers must be 18 years or older, in general good health, and cannot be taking other medications intended to prevent COVID-19. Women who wish to volunteer must not be pregnant or breastfeeding.

Billions of people in the world still need to vaccinated. The more vaccines that are available, the sooner we can end the pandemic. Plus we also need vaccines that can work for many different kinds of people and that can be easily distributed and administered, particularly in developing countries. We can’t do this research without the help of study volunteers.


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